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Top Quality Cosmetic Grade 99% 4-Butylresorcinol 18979-61-8 with Best Price

CAS No.:18979-61-8
Place of Origin:China
Appearance:White fine powder
MF:C10H14O2
Purity:>99.5%
Certificate:COA MSDS TDS
Free Samples

CATEGORY

4-Butylresorcinol—commonly known as “577”—is a highly effective skin-whitening active ingredient classified as a resorcinol derivative. Its chemical name is 1-butyl-3-hydroxyphenol, and its molecular formula is C₁₀H₁₄O₂. As a novel tyrosinase inhibitor, 4-butylresorcinol blocks melanin production by competitively inhibiting tyrosinase activity; it also possesses antioxidant and anti-inflammatory properties.

This ingredient was originally developed by the Japanese company POLA and was launched in 1998 under the registered trade name “Rucinol.” Compared to traditional whitening agents such as hydroquinone, arbutin, and kojic acid, 4-butylresorcinol demonstrates superior skin penetration and significantly more potent inhibitory effects, while presenting relatively fewer side effects. Consequently, it is widely utilized in high-end skin-whitening products and clinical dermatological treatments.

Product picture:

Function

4-Butylresorcinol is a potent competitive inhibitor of tyrosinase. It binds directly to the enzyme, occupying its active site and thereby blocking the conversion of tyrosine into dopaquinone, effectively inhibiting melanin synthesis at its source.

In addition to inhibiting melanin production, 4-butylresorcinol exhibits significant antioxidant activity. It scavenges free radicals and mitigates oxidative stress-induced skin damage, thereby supporting skin brightening and delaying skin aging.

4-Butylresorcinol is widely utilized in products such as brightening serums, spot-correcting creams, and anti-dark spot lotions; it is frequently formulated in combination with ingredients like niacinamide and Vitamin C to enhance its skin-brightening efficacy.

In clinical dermatology, 4-butylresorcinol is employed in the treatment of pigmentary disorders, such as melasma and post-inflammatory hyperpigmentation.

Product Specifications:

ITEM	SPECIFICATION	TEST METHOD
Active Ingredeints
Assay	NLT 99%	HPLC
Physical Control
Identification	Positive	TLC
Appearance	White powder	Visual
Odor	Characteristic	Organoleptic
Taste	Characteristic	Organoleptic
Sieve Analysis	100% pass 80 mesh	80 Mesh Screen
Moisture Content	NMT 1.0%	Mettler toledo hb43-s
Chemical Control
Arsenic (As)	NMT 2ppm	Atomic Absorption
Cadmium(Cd)	NMT 1ppm	Atomic Absorption
Lead (Pb)	NMT 3ppm	Atomic Absorption
Mercury(Hg)	NMT 0.1ppm	Atomic Absorption
Heavy Metals	10ppm Max	Atomic Absorption
Microbiological Control
Total Plate Count	10000cfu/ml Max	AOAC/Petrifilm
Salmonella	Negative in 10 g	AOAC/Neogen Elisa
Yeast & Mold	1000cfu/g Max	AOAC/Petrifilm
E.Coli	Negative in 1g	AOAC/Petrifilm
Salmonella	Negative	AOAC
Staphylococcus	Negative	AOAC