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2,5-Dimethoxytetrahydrofuran (THFDM) is an important organic compound. At room temperature, it appears as a colorless to pale yellow transparent liquid characterized by a low boiling point, high solubility, and excellent fluidity, earning it the reputation of being a “universal solvent.” As a versatile chemical raw material, this substance finds extensive application in fields such as pharmaceuticals, disinfection and preservation, and industrial materials.

2,5-Dimethoxytetrahydrofuran is a crucial raw material for the synthesis of tropinone, which, in turn, serves as a key intermediate in the production of the anticholinergic drug atropine sulfate. During the synthesis of tropinone, the succinaldehyde generated from the hydrolysis of this compound acts as one of the core precursors for constructing the tropane skeleton.
Under acidic or neutral conditions, this substance exhibits potent bactericidal activity, making it an excellent disinfectant. It is frequently utilized as a precursor for succinaldehyde and is widely employed in the formulation of disinfectants for surgical instruments; it effectively eradicates bacterial spores, thereby ensuring the sterility of medical devices.
Renowned in the industrial sector as a “universal solvent” due to its excellent solvency and low volatility, 2,5-dimethoxytetrahydrofuran finds extensive application across the plastics, rubber, coatings, adhesives, inks, and textile industries. It significantly enhances the solubility and homogeneity of resins, thereby improving overall product performance.
In the photographic industry, it serves as a hardener for photographic films, bolstering the mechanical strength of the photosensitive emulsion layer and preventing it from detaching during the development process.
Furthermore, within the emerging field of electronic chemicals, this substance can be incorporated as an additive into lithium-ion battery electrolytes, where it contributes to enhancing both the battery’s cycle life and its high-temperature stability.
Application Areas:
Fine Chemicals: Surfactants, Wetting Agents, Plasticizers, Decoloring Agents
Agriculture: Insecticides
Packaging Industry: Bottles, Films
Technical Specifications:
| Name | 2,5-Tetrahydrofurandimethyl |
| CAS | 104-80-3 |
| Melting point | -70℃ |
| Boiling Point | 230 ± 5℃ |
| Relative Density | 1.130 g/cm3 at 25℃ |
| Stability | Hygroscopic, store in a sealed container at low temperature. |
Package:
1kg /25kg Bucket
Palletized Shipping
Lead Time: 1-7 Days
Shipping Methods: Sea/Air/Express delivery

