As an anti-caries active ingredient, it is often added to toothpaste as a substitute for or partial replacement of sodium fluoride. Compared to sodium fluoride, sodium monofluorophosphate has better compatibility with abrasives in toothpaste (such as dicalcium phosphate), is less prone to side reactions, and does not stain teeth. In addition, it is also used in daily oral care products such as mouthwash to help prevent tooth decay and gingivitis.
In the industrial field, sodium monofluorophosphate is used to remove oxides and dirt from metal surfaces, possessing both cleaning and corrosion-inhibiting functions.
In wood preservation, it can be used as a preservative to prevent wood decay and insect infestation.
In glass manufacturing, it is used as a flux and opacifier in opalescent glass and special optical glass.
In agriculture, it was once used to control certain crop pests and diseases, but its application is limited due to environmental reasons.