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Line‑angle drawing of a brominated, methyl-substituted pyridine ring: a six-member aromatic ring with one nitrogen, showing Br and CH3 substituents.

3-Pyridyl bromide CAS 626-55-1

CAS No.:134-62-3
Purity:99%
Place of Origin:Henan China
MF:C12H17NO
Appearance:Clear colorless to pale brown Liquid
Certification:MSDS,COA,TDS
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3-Bromopyridine is an organic compound with the chemical formula C₅H₄BrN, belonging to the halopyridine class of compounds. It is a colorless to pale yellow liquid or solid with a characteristic pungent odor. As an important intermediate in organic synthesis, 3-bromopyridine has wide applications in the pharmaceutical, pesticide, and materials science fields.

In the pharmaceutical industry, 3-bromopyridine is a key intermediate in the synthesis of many drugs, such as the non-nucleoside reverse transcriptase inhibitor nevirapine, the antidepressant zimetidine hydrochloride, and the neurological drug proclamoprofen. In the pesticide field, it is used to synthesize herbicides such as nicosulfuron and insecticides such as chlorantraniliprole. Furthermore, 3-bromopyridine can be used to prepare optoelectronic materials, such as as a precursor for luminescent materials or organic semiconductors. The bromine atom in its molecule has good reactivity and can participate in various coupling reactions (such as the Suzuki and Heck reactions) to construct complex molecular structures.

 

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3-Pyridyl bromide
3 Pyridyl bromide
Function

3-Bromopyridine is a crucial building block in the synthesis of many drugs. In antiviral drugs, it is a key intermediate in the synthesis of the non-nucleoside reverse transcriptase inhibitor nevirapine. Nevirapine is a first-line drug for treating HIV, acting by directly inhibiting HIV reverse transcriptase activity. In nervous system drugs, it is used in the synthesis of the antidepressant Cimitapride and the antipsychotic Pipotiazine. Furthermore, it is used as an intermediate in the synthesis of quinolone antibacterial drugs (such as balofloxacin), specifically 3-methylaminopiperidine.

In the pesticide field, 3-Bromopyridine is used in the synthesis of various highly effective pesticides. It is an important raw material for the synthesis of sulfonylurea herbicides such as Nicosulfuron, a cornfield-specific herbicide with excellent control of grassy weeds. Meanwhile, 3-bromopyridine is also a key intermediate in the synthesis of neonicotinoid insecticides (such as imidacloprid) and diamide insecticides (such as chlorantraniliprole).

3-bromopyridine and its derivatives also have applications in the field of optoelectronic materials. It can be used as a precursor to synthesize conjugated polymers or small organic molecules with specific structures through coupling reactions, which are then used to prepare optoelectronic functional materials such as organic light-emitting diodes (OLEDs) and organic semiconductors.

 

Technical Specifications:

Appearance
Clear colorless to pale brown Liquid
Content
99% min(GC)
M.P.
-27°C
Moisture
0.20% max

 

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1Kg / 200Kg Bucket

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3-Pyridyl bromide package
3 Pyridyl bromide package

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