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Cycloastragenol

Premium 98% Cycloastragenol Powder (CAS 78574-94-4) – High Purity Astragalus Root Extract

CAS No.:78574-94-4
Place of Origin:China
Appearance:White Powder
MF:C30H50O5
Purity:5%-98%
Certificate:COA MSDS TDS
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Cycloastragenol (CAG) is a tetracyclic triterpenoid compound extracted from the roots of *Astragalus membranaceus*—a traditional Chinese medicinal herb—and serves as the aglycone form of astragalosides (such as Astragaloside IV). As the only currently validated telomerase activator among natural products, cycloastragenol attracts significant attention in the field of anti-aging research; it functions by activating telomerase activity to induce telomere elongation, thereby delaying the process of cellular senescence. Furthermore, cycloastragenol exhibits a diverse range of pharmacological activities, including immunomodulatory, anti-inflammatory, and antioxidant effects, as well as cardiovascular protection and the promotion of wound healing. In recent years, driven by advancements in bioengineering technologies, the heterologous synthesis of cycloastragenol has been successfully achieved through metabolic engineering in yeast, opening up new avenues for its large-scale application.

 

Product picture:
Cycloastragenol
Cycloastragenol

 

Function

Due to its unique pharmacological activities, cycloastragenol has demonstrated potential therapeutic value across various disease domains. In the realm of anti-aging, it extends telomere length in fibroblasts, enhances cellular proliferative capacity, promotes the proliferation and migration of epidermal stem cells, and accelerates wound healing.

Regarding immune modulation, it stimulates the proliferation and differentiation of T lymphocytes and enhances the activity of natural killer cells, thereby exhibiting potential therapeutic efficacy against chronic HIV-1 infection.

Furthermore, cycloastragenol exerts protective effects on the cardiovascular system by improving vascular endothelial function and reducing the risk of atherosclerosis; it mitigates hepatic fibrosis; and within the nervous system, it promotes the proliferation of neural stem cells and protects neurons against ischemic injury.

These characteristics position it as a promising candidate ingredient for the development of therapeutic agents targeting diseases associated with telomere dysfunction, neurodegenerative disorders, and immunodeficiency diseases.

 

Product Specifications:

Assay data
Customization
Odor & taste
Characteristic
Particle size
NLT 95% through 80 meshes
Loss on drying
7.0% max.
Heavy metals
10ppm max.
Pb
≤3ppm
As
≤2ppm
Cd
≤1ppm
Hg
≤0.1ppm
Total aerobic count
Not more than 10000cfu/gram
Yeast & Mold count
Not more than 100cfu/gram
E. Coli
None detected
Salmonella
None detected
S. aureus
None detected

 

Package:

1kg/25kg Bucket

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Lead Time: 1-7 Days

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Cycloastragenol package
Cycloastragenol package

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